Agenda

Please note that all times listed currently reflect US Eastern Time (ET). The schedule is subject to change. Presentations are live or pre-recorded followed by live group Q&A

Tuesday, July 27th, 2021
 
Time Event
10:00 am – 10:15 am Welcome and Introductions:
Charles Stephensen (USDA/WHNRC/UC Davis) & Raz Shaikh (University of North Carolina, Chapel Hill)
10:15 am – 11:00 am Keynote Address: Nicole Baumgarth (University of California, Davis)
Regulation of antimicrobial humoral immunity
11:00 am – 11:15 am Break
11:15 am – 1:00 pm Session 1: Obesity: Impacts on Innate and Adaptive Immunity
Chair: Raz Shaikh (University of North Carolina, Chapel Hill)
11:15 am – 11:35 am Alyssa Hasty (Vanderbilt University)  
Adipose Immunity in Weight Loss and Cycling
11:35 am – 11:55 am Daniel Winer (Buck University)
Insulin Receptor Control of Adaptive Immunity
11:55 am – 12:15 pm Arion Kennedy (North Carolina State University)
Unraveling T cell Activation in Obesity Associated Fatty Liver Disease
12:15 pm – 12:35 pm Nancie Jo MacIver (Duke University)
Molecular mechanisms of T-cell dysfunction in malnutrition
12:35 pm – 12:45 pm Natalie Harasymowicz (Washington University in St. Louis)
Gene Therapy for fat-1 Prevents Obesity-Induced Inflammation and Cellular Senescence And Increases the Content of Anti-Inflammatory Macrophages
12:45 pm – 1:00 pm Questions and Answers 
1:00 pm – 2:15 pm Break
1:15 pm – 2:00 pm Meet the Experts Session 
Room 1 - Setting up and using a gnotobiotic mouse facility for dietary studies. Presentations by Dr. Laxmi Yeruva and Dr. Timothy Hand, followed by discussion.
Room 2 - Using dietary intake data to characterize risk of inflammation. Presentations by Dr. Edward Giovannucci and Dr. Fred Tabung, followed by discussion.
Room 3 - Use of machine learning in nutrition research. Presentation by Dr. Danielle Lemay, followed by discussion.
2:15 pm – 4:00 pm Session 2: Diet and Infection in the Age of COVID
Chair: Melinda Beck
(University of North Carolina, Chapel Hill)
2:15 pm – 2:35 pm Linda Saif (The Ohio State University)
Nutritional impacts on immune response to rotavirus infection
2:35 pm – 2:55 pm Raz Shaikh (UNC, Chapel Hill)
Obesity drives a dysregulated specialized pro-resolving mediator signature: Implications for viral infection
2:55 pm – 3:15 pm Melinda Beck (UNC, Chapel Hill)
Obesity and Influenza vaccination: Lessons learned for COVID-19
3:15 pm – 3:35 pm Daniela Frasca (University of Miami)
Obesity, aging, and B-cells
3:35 pm – 3:45 pm Sarah Price (University of Louisville)
Got Zinc? A Role for Yersiniabactin in Zinc Acquisition during Yersinia pestis Infection
3:45 pm – 4:00 pm Questions and Answers
4:00 pm – 4:15 pm Break
4:15 pm – 5:30 pm Poster Session 1 - Posters will be available online for viewing a few days prior to the virtual SRC; session time will be devoted to Q&A between poster presenters and attendees
5:30 pm – 6:30 pm Planning the Next Conference - (via zoom link) All conference attendees are invited to discuss plans for collecting feedback on this conference and planning for a future conference.
 
Wednesday, July 28th, 2021
  
Time Event
10:00 am – 10:15 am Day Two: Welcome Address and Summary of Day One
10:15 am – 11:45 am Session 3: Nutritional Immunity: The Battle for Nutrients Between Hosts and Bacteria
Chair: Charles Stephensen (USDA, WHNRC/UC Davis)
10:15 am – 10:35 am Eric Skaar (Vanderbilt University)
Transition metals and virulence in bacteria
10:35 am – 10:55 am Manuela Raffatellu (University of California, San Diego)
Nutritional Immunity in the inflamed gut
10:55 am – 11:15 am Hal Drakesmith (University of Oxford)
The battle for iron: A key determinant of the outcome of infection
11:15 am – 11:25 am Jeanette Miller (Vanderbilt University)
The Function of a Bacterial Lytic Transglycosylase in Mitigating Zinc Dysregulation
11:25 am – 11:45 am Questions and Answers
11:45 am – 12:00 pm Break
12:00 pm – 1:45 pm Session 4: Diet, Microbiome, and Immunity During Infancy 
Chair: Sarah Comstock (Michigan State University)
12:00 pm – 12:20 pm Timothy W. Hand (University of Pittsburgh)
The role of maternal IgA in infant gut health
12:20 pm – 12:40 pm Laxmi Yeruva (Arkansas Children's Nutrition Center)
Breastmilk and immunity in the infant: Lessons from animal models
12:40 pm – 1:00 pm Marcia Monaco (University of Illinois)
A swine model of colitis for mechanistic understanding of microbiota and immunity
1:00 pm – 1:20 pm Valerie Verhasselt (University of Western Australia)
Antigen shedding in human milk: a key for immune system education
1:20 pm – 1:30 pm Akila Rekima (University of Western Australia)
Colostrum drives the development of successful anti-helminth immune defenses
1:30 pm – 1:45 pm Questions and Answers
1:45 pm – 3:00 pm Break
2:00 pm – 2:45 pm Career Development Session for Early Career Scientists - Two senior scientists (Drs. Stephen Hursting and Charles Stephensen) and two mid-career scientists (Drs. Raz Shaikh and Sarah Comstock) discuss how to succeed in a scientific career.
3:00 pm – 3:45 pm Poster Session 2 - Posters will be available online for viewing a few days prior to the virtual SRC; session time will be devoted to Q&A between poster presenters and attendees
3:45 pm – 4:00 pm Break
4:00 pm – 5:45 pm Session 5: Prebiotics, Probiotics and Immune Health
Chair: Margherita Cantorna
(Penn State University)
4:00 pm – 4:20 pm Sarah Comstock (Michigan State University)
Prebiotic dietary modifications to decrease intestinal inflammation in adult humans
4:20 pm – 4:40 pm Margherita Cantorna (Penn State University)
Mechanisms underlying vitamin D control of mucosal infection
4:40 pm – 5:00 pm Adam Moeser (Michigan State University)
Early nutrition, stress, the microbiome, and intestinal mast cell function
5:00 pm – 5:20 pm Danielle Lemay (USDA, Western Human Nutrition Research Center/UC Davis)
Dietary fiber, microbiome and intestinal inflammation in healthy humans
5:20 pm – 5:30 pm Yasmine Bouzid (University of California, Davis)
Adequate intake of dietary fiber is associated with lower gastrointestinal inflammation in healthy U.S. adults
5:30 pm – 5:45 pm Questions and Answers
 
Thursday, July 29th, 2021
 
Time Event
10:00 am – 10:15 am Day Three: Welcome Address and Summary of Day Two
10:15 am – 11:00 am Keynote Address: Stephen Hursting (UNC, Chapel Hill)
Breaking the Obesity-Cancer Link: A Mechanistic Perspective
11:00 am – 11:15 am Break
11:15 am – 1:00 pm Session 6: Environmental and Nutritional Stressors on Immunity 
Chair: Simin Meydani (USDA/ HNRCA/Tufts University)
11:15 am – 11:35 am Cheryl Rockwell (Michigan State University)
The food preservative tert-butylhydroquinone exacerbates the T cell response to food allergen
11:35 am – 11:55 am Michael B. Fessler (National Institute of Environmental Health Sciences)
Oxysterols Coordinate Lipid and Inflammatory Homeostasis in the Lung
11:55 am – 12:15 pm Philip Calder (University of Southampton)
n-3 PUFA and adaptive immunity in humans
12:15 pm – 12:35 pm Kym Gowdy (The Ohio State University)
Dietary Omega-3 Polyunsaturated Fatty Acids Modulate the Pulmonary Response to Environmental Exposures
12:35 pm – 12:45 pm Jerry Lio (Ohio State University)
Vitamin C Potentiates Plasma cell Differentiation via TET-mediated DNA Modifications at a Novel Prdm1 Distal Element
12:45 pm – 1:00 pm Questions and Answers
1:00 pm – 2:00 pm Break
1:15 pm – 1:45 pm Sponsored Event (National Dairy Council) - Dr. Chris Cifelli, VP for Research, will describe the Council's program for research funding and provide an overview of recently funded projects related to diet and inflammation.
2:00 pm – 3:45 pm Session 7: Dietary Patterns, Microbiota, Inflammation/Immunity and Disease Risk
Chair: Jimmy Crott (USDA/Human Nutrition Research Center on Aging/Tufts University)
2:00 pm – 2:20 pm Fred Kinyuy Tabung (The Ohio State University)
Dietary indices of inflammation and cancer risk
2:20 pm – 2:40 pm Edward Giovannucci (Harvard University)
Inflammatory diets, microbiome and colon cancer risk
2:40 pm – 3:00 pm Charles Stephensen (USDA, WHNRC/UC Davis)
Association of Healthy Eating Index scores with inflammation and immune activation in healthy adults
3:00 pm – 3:20 pm Stine M. Ulven (University of Oslo)
Dietary fat, metabolomics and inflammation assessed by gene expression profiling
3:20 pm – 3:30 pm Qi Jin (The Ohio State University)
Hyperinsulinemic and pro-inflammatory dietary patterns are associated with increased risk of total and site-specific cancers among postmenopausal women
3:30 pm – 3:45 pm Questions and Answers
3:45 pm – 4:00 pm Break
4:00 pm – 5:30 pm Session 8: Diet, Intestinal Inflammation and Cancer
Chair: Stephen Hursting
(UNC, Chapel Hill)
4:00 pm – 4:20 pm Jimmy Crott (USDA, HNRCA)
Dietary fat, microbiome, inflammation and intestinal tumorigenesis
4:20 pm – 4:40 pm Connie Rogers (Penn State University)
Role of changes in energy balance and related nutritional factors on inflammation
4:40 pm – 5:00 pm Bill Murphy (UC Davis)
Effect of obesity-related inflammation on immunotherapy in cancer
5:00 pm – 5:10 pm Michael Coleman (UNC Chapel Hill)
β-Hydroxy-β-Methylbutyrate synergizes with cytotoxic chemotherapy and immunotherapy in a mouse model of pancreatic cancer
5:10 pm – 5:30 pm Questions and Answers
5:30 pm – 5:45 pm Wrap-up by Conference Organizers